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A potential new treatment for neuroblastoma
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A potential new treatment for neuroblastoma

We welcome the news that a potential new treatment for children with neuroblastoma will be advanced to clinical trial and reach more young cancer patients.

Researchers have found an indirect way to target N-Myc, a gene that occurs in aggressive forms of neuroblastoma. They found that a new drug, fadraciclib, is effective at blocking N-Myc activity by switching off the production of N-Myc and a clinical trial for children with high-risk neuroblastoma is due to open by the end of 2020.

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Accelerating drug development for neuroblastoma
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Accelerating drug development for neuroblastoma

An international forum of leading scientists from the UK, Europe and USA, funded by national charity Neuroblastoma UK, prioritises drug development and strategies for new treatment trials for children with neuroblastoma.

In the September edition of European Journal of Cancer, Dr Lucas Moreno from Vall d’Hebron Hospital, Barcelona, and a team of international scientific and clinical experts published an agreed list of genetic targets and drugs that should be advanced for early-phase paediatric clinical trials, following the second Neuroblastoma New Drug Development Strategy (NDDS) forum.

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Press release: Charities fund new clinical trial to help children with cancer
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Press release: Charities fund new clinical trial to help children with cancer

Neuroblastoma UK and Solving Kids Cancer have awarded a grant to enable the SIOPEN High-Risk Neuroblastoma Clinical Trial 2 (HR-NBL2) to open in the UK, it is anticipated to open in early 2021.

This Phase 3 clinical trial will offer children in the UK, with a diagnosis of high-risk neuroblastoma, to have the same opportunities as children across Europe and take part in this pan-European study.

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NHS consultation: Children’s Cancer Services
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NHS consultation: Children’s Cancer Services

NHS England launched a 60-day consultation on 5 June 2019, to seek views on proposed changes to children's cancer services. The consultation runs until Sunday 4 August 2019. Read our response and find out how you can give your feedback.  

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